Prophylaxis against anaerobic infections in abdominal (especially colorectal) & gynaecological surgery Adult 400 mg 8 hrly.
Childn 7.5 mg/kg 8 hrly.
Established anaerobic infection Adult Initially 800 mg, followed by 400 mg 8 hrly.
Childn 7.5 mg/kg 8 hrly. Duration: 7 days.
Urogenital trichomoniasis Adult & childn >10 yr 200 mg tds for
7 days
or 800 mg
in the morning & 1,200 mg in the evening for 2 days
or 2 g as single dose for 1 day,
childn 7-10 yr 100 mg tds for 7 days,
3-7 yr 100 mg bd for 7 days,
1-3 yr 50 mg tds for 7 days.
Bacterial vaginosis Adult & childn >10 yr 400 mg bd for 7 days
or 2 g as single dose for 1 day.
Invasive intestinal disease in susceptible subject Adult & childn >10 yr 800 mg tds for 5 days,
7-10 yr 400 mg tds for 5 days,
3-7 yr 200 mg qds for 5 days,
1-3 yr 200 mg tds for 5 days.
Intestinal disease in less susceptible subjects & chronic amoebic hepatitis Adult & childn >10 yr 400 mg tds for 5-10 days,
7-10 yr 200 mg tds for 5-10 days,
3-7 yr 100 mg qds for 5-10 days,
1-3 yr 100 mg tds for 5-10 days.
Amoebic liver abscess Duration: 5 days.
Symptomless cyst passers Adult & childn >10 yr 400-800 mg tds for 5-10 days,
7-10 yr 200-400 mg tds for 5-10 days,
3-7 yr 100-200 mg qds for 5-10 days,
1-3 yr 100-200 mg tds for 5-10 days.
Giardiasis Adult & childn >10 yr 2 g once daily for 3 days,
7-10 yr 1 g once daily for 3 days;
3-7 yr 600-800 mg once daily for 3 days,
1-3 yr 500 mg once daily for 3 days.
Acute ulcerative gingivitis Adult & childn >10 yr 200 mg tds for 3 days,
7-10 yr 100 mg tds for 3 days,
3-7 yr 100 mg bd for 3 days,
1-3 yr 50 mg tds for 3 days.
Acute dental infection Adult & childn >10 yr 200 mg tds for 3-7 days.
Leg ulcers & pressure sores Adult & childn >10 yr 400 mg tds for 7 days.
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